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Test paper for dental students - Hematocrap pathology test 4

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Hematocrap pathology
Dental Abbreviations
Dental terminology
Anatomy 1
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Neck Anatomy
Nitrous Oxide
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Question Answer
What are the most common leukemias?
What are the two major types of leukemias?
Flow cytometry and cluster of differentiation are lab procdures to detect what?
As a result of leukemia, what lab findings do you find in the PERIPHERAL blood?
What is the most common eventual cause of death in patients w/ leukemias?
Why does anemia, recurrent infection and bleeding occur in leukemia, a WBC disorder?
T or F: most cases of luekemias are caused by HTLV-1.
What clotting factor is congenitally deficient in Hemophilia A?
Hemophilia A & B are what type of bleeding disorders?
What are 2 anticoagulants that inhibit coagulation factor production?
DIC is responsible for what clotting factor disease?
What does the anticoagulant coumadin do?
Why is chronic liver disease also known as hypofibrinogenemia
Why does chronic liver disease cause inadequate production of clotting factors?
________ clotting factor deficiencies are caused by inadequte production, excessive consumption, inhibition by anticoagulants.
Aspirin, NSAIDS, ESRD (accumulation of metabolites) and Plavix all lead to ___________
Two forms of Qualitative platelet bleeding disorders:
DIC (yes, that's right), (Shock, infection tumors, injured endothelial cells, activation of coagulation system, widespread thrombi, fibrinolysis, bleeding) all contribute to __________.
Hypersplenism leads to _____________.
Autoimmune destruction, SLE, HIV,Heparin-induced thrombocytopenia, all contribute to _________.
Aplastic anemia, leukemia, infecious agents (ie rubella), and drugs (interfere w/ megakaryocytes) are contributory to ______________.
The etiology of this disease is: Decreased production of platelets, Increased loss of platelets
Petechiae, and ecchymoses (skin+mucous membranes) are signs of what bleeding disorder?
What occurs when platelet levels reach below 20,000/mm3?
What platelet level characterizes thrombocytopenia?
This type of bleeding disorder can be qualitative or quantitative
What bleeding disorder? Petechiae & eccymoses, skin, mucous membranes, after minor trauma/spontaneously; normal platelet count, PT & PTT bleeding time
What bleeding disorder? Autoimmune vasculitidies, allergic drugs rxns.
Scurvy, Amyloid, chronic systemic steroid use, inherited conditions infectious causes, and aging can all cause what type of bleeding disorder?
What are 3 mechanisms of vascular bleeding disorders?
What is the international normalized ratio (INR)?
Increased PTT is shown with a defect of factors __,___,___,___,___,___,prothrombin, fibrinogen or acquired antibody that interferes with intrinsic pathway.
Assesses the integrity of the INTRINSIC and common clotting pathways
What lab evaluation? Time required for plasma to clot
Deficiency of factors V, VII, or X, prothrombin, or fibrinogen is a diagnosis of ____________ Prothrombin time (PT)
What lab evaluation? Tests adequacy of Extrinsic and common coagulation pathways
What lab evaluation? Time needed for plasma to clot in presence of exogenous source of thromboplastin and calcium
What is the normal platelet count?
Which laboratory evaluation? In vivo assessment of platelet response to vascular injury, normal=several minutes, elevated=defect in platelet # or function
What disease? Bone destruction, punched out radiolucencies, soft tissue lesions, children.
What other variants of Multiple myeloma are there?
What disease? Lab findings: monoclonal Ig spike, Bence-Jones Protein, Abnormal plasma cells, amyloid deposition, light chain proteinuria
What disease? Bone pain & destruction, hypercalcemia, metastatic calcification, renal damage, bone fractures
What disease? Adults (45-50 yrs), NOT in children, bone destruction, punched out radiolucencies
What WBC disorder involves malignant plasma cells?
T or F: bone marrow biopsy must be performed to confirm diagnosis of leukemia
Desmopressin, factor VIII, XI concentrates are used in hospital based Tx for patients with _____________
For warfarin patients, INR must be below __________for minor surgeries
________ heparin patients must be hospitalized for Tx, while __________ heparin patients are generally not a concern
T or F: Plavix is a concern for inc. bleeding during Tx
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