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Test paper for dental students - Virology test (2005) Part 4

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Question Answer
Which pattern of viral pathogenesis? Follows acute infection, virus persists in noninfectious form w/ intermittent periods of reactivation & shedding.
Which pattern of viral pathogenesis? Viral infection which is rapidly cleared by host immune response.
What are the five patterns of Viral Pathogenesis?
Which virus(es) are: Relaxed circular, partially duplexed DNA virus? (1)
Which virus(es) are: Double-stranded RNA virus? (2)
Which virus(es) are: Segmented Negative Strand RNA virus (1)
Which virus(es) are: Non-segmented negative-strand RNA virus (3)
Which virus(es) are: Retrovirus (1)
Which virus(es) are: Positive-strand RNA virus coding for one or more subgenomic mRNAs? (4)
Which virus(es) are: Positive-strand RNA virus coding for one genome-sized RNA? (2)
Which virus(es) are: Single-stranded DNA virus? (1)
Which virus(es) are: double-stranded DNA virus that replicates in the cytoplasm?(1)
Which virus(es) are: double-stranded DNA virus that replicates in the nucleus (circular or linear) (3)
T or F: Retroviruses can reproduce without cell death.
T or F: The process of viral budding alone will cause cell death.
What are the 2 ways for release of the virus from a cell?
What stages make up the "eclipse (flat line)" state of the one-step growth curve?
Where does assembly take place for the influenza virus?
Where does assembly take place for the herpes virus?
What is the location in the cell where assembly initiates?
During encapsidation, Individual structural subunits or protomeres are preformed into __________ in preparation for final assembly.
T or F: During encapsidation, self-assembly of component parts occurs in a random fashion
What is a long polypeptide chain that is translated from a single transcript with a single ribosome binding site?
What is the process in RNA that removes intervening sequences that do not encode for protein product?
The coding DNA strand is always a ________ polarity.
RNA molecules which are complementary to mRNA have a ______ polarity.
mRNA strands have a ______ polarity.
In order for the virus to replicate, what must it present to the cell?
Most DNA viruses replicate in the ___________.
Most RNA viruses replicate in the ___________.
What is the KEY event in virus replication?
During membrane fusion, the _________ fuses with the plasma membrane of the host cell, thus releasing the __________ into the cell.
What process does the Herpesvirus undergo to enter the cell and undergo de-coating?
What is the portion of the virus called that is surrounded by the envelope?
What is the portion of the cell membrane called that breaks off and surrounds the virus during receptor-mediated endocytosis?
The influenza virus is critically dependent on what in order to un-coat and begin replicating?
What is the process called in the removal of the protective envelope and/or capsid?
T or F: The virus can begin replication prior to dismantleling.
What type of entry: Virion envelope fuses with cellular membrane
What type of entry: results in accumulation of virus particles inside cytoplasmic vesicles (ie influenza this way)
What type of entry: entire virus crosses plasma membrane (non-enveloped)
What are the three types of entry?
T or F: Penetration is energy dependent (not that type of penetration sickos)
How do neutralizing antibodies work?
Differences in host range and tissue tropism are due most often to the presence or absence of ___________.
What is adsorption enhanced by?
Viral _________ are examples of antireceptor molecules
In the process of adsorption, what are the cellular receptors composed of?
What are the 3 general stages of initiation of infection?
What are the 3 steps in PCR?`
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